ProSci

CD72.1 Antibody [10.1.D2] (APC)

Product Code:
 
PSI-98-844
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Mouse
Antibody Isotype:
 
IgG2b
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
[10.1.D2]
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Flow Cytometry
Shipping:
 
blue ice
Storage:
 
Store vial at 2-8˚C
1 / 1
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PSI-98-844-0.1mg0.1mg£597.00
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Further Information

Additional Names:
Lyb-2.1, CD72a, Lyb-2a
Application Note:
CD72.1 Antibody [10.1.D2] for use in flow cytometry assays.
Background:
Murine CD72.1 (Lyb-2.1), a type II integral membrane glycoprotein and a member of the C-lectin family of cell surface receptors, is a differentiation antigen of B cells and is found in mouse strains expressing the Lyb-2.1 allotype. CD72.1 is the ligand of CD5 which is distributed on all T cells and a small number of B cells. The 10.1.D2 monoclonal antibody blocks binding of CD5 to CD72 on the B cell surface which leads to inhibition of the positive signal resulting from CD5/CD72 pairing. However, 10.1.D2 can itself trigger a positive signal by binding CD72.
Buffer:
Supplied in PBS/NaN3 and a stabilizing agent
Concentration:
0.1 mg/mL
Conjugate:
APC
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
DBA/2 mouse spleen cells
NCBI Gene ID #:
12517
NCBI Official Name:
CD72 antigen
NCBI Official Symbol:
Cd72
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
P21855
Research Area:
Immunology,Signal Transduction
SPECIFICITY:
CD72.1
Swissprot #:
P21855
User NOte:
Optimal dilutions for each application to be determined by the researcher.