Further Information
NAD(P)H dehydrogenase [quinone] 1, Azoreductase, DT-diaphorase, DTD, Menadione reductase, NAD(P)H:quinone oxidoreductase 1, Phylloquinone reductase, Quinone reductase 1, QR1, NQO1, DIA4, NMOR1
Western blot: 1-3 ug/ml
Provided assay concentrations are suggestions only, NQO1 antibody titration may be required for optimal results.
NAD(P)H:quinone oxidoreductase is an enzyme that catalyzes the two-electron reduction of quinones to hydroquinones, resulting in the activation or deactivation of the hydroquinone. Increased expression of NQO1 is seen in tumors of the breast, liver and colon and NSCLC or ?non-small cell lung cancer,? suggesting a role in tumor development and possibly treatment. NQO1 has also been linked to Alzheimer's disease, found to be upregulated in response to the oxidative stress of the AD process.
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
0.5 mg/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
A recombinant protein fragment from the C-terminal region of human NQO1 was used as the immunogen for this antibody.
1728
NAD(P)H dehydrogenase, quinone 1
NQO1
Homo sapiens
Liquid
Protein A affinity chromatography
Obesity,Signal Transduction
P15559
Optimal dilutions for each application to be determined by the researcher