Ubiquitin Antibody

Western blot: 1:500-1:2000

Optimal dilution of the Ubiquitin antibody should be determined by the researcher.

The UBB gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. [RefSeq]

Purified

Antibody in PBS with 0.02% sodium azide and 50% glycerol

A synthetic peptide specific to human Ubiquitin / UBB was used as the immunogen for the Ubiquitin antibody.

This Ubiquitin antibody is available for research use only.

Affinity purified

Human

P0CG47