ProSci

MSLN Antibody

Product Code:
 
PSI-15-369
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Shipping:
 
Blue Ice or RT
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunohistochemistry of paraffin-embedded rat kidney using MSLN Antibody (15-369) at dilution of 1:100 (40x lens).
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Immunofluorescence analysis of U2OS cells using MSLN antibody (15-369). Blue: DAPI for nuclear staining.
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Immunohistochemistry of paraffin-embedded rat kidney using MSLN Antibody (15-369) at dilution of 1:100 (40x lens).
Immunofluorescence analysis of U2OS cells using MSLN antibody (15-369). Blue: DAPI for nuclear staining.

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PSI-15-369-50uL50uL£433.00
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Further Information

Additional Names:
MSLN, CAK1, MPF, SMR, SMRP
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:200

IF: 1:50 - 1:100
Background:
This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 37-296 of human MSLN (NP_001170826.1).
NCBI Gene ID #:
10232
NCBI Official Name:
mesothelin
NCBI Official Symbol:
MSLN
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Affinity purification
Research Area:
Cancer, Immunology
Swissprot #:
Q13421
User NOte:
Optimal dilutions for each application to be determined by the researcher.