Antibody Clonality:
Polyclonal
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
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This product comes from:
United States.
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Further Information
single-minded homolog 2, short isoform, single-minded homolog 2, class E basic helix-loop-helix protein 15, OTTHUMP00000109044, bHLHe15, SIM, MGC119447, single-minded homolog 2 (Drosophila), SIM2, BHLHE15
WB: 1:500 - 1:2000
IHC: 1:100 - 1:200
This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 342-525 of human SIM2 (NP_033664.2).
6493
single-minded family bHLH transcription factor 2
SIM2
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 56kDa
Affinity purification
Cancer, Neuroscience, Transcription
Q14190
Optimal dilutions for each application to be determined by the researcher.