ProSci

FXN Antibody

Product Code:
 
PSI-16-775
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Shipping:
 
Blue Ice or RT
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
1 / 5
Immunohistochemistry of paraffin-embedded human mammary cancer using FXN / Frataxin antibody (16-775) at dilution of 1:100 (40x lens).
2 / 5
Immunohistochemistry of paraffin-embedded human colon using FXN / Frataxin antibody (16-775) at dilution of 1:100 (40x lens).
3 / 5
Immunohistochemistry of paraffin-embedded human lung cancer using FXN / Frataxin antibody (16-775) at dilution of 1:100 (40x lens).
4 / 5
Immunohistochemistry of paraffin-embedded rat lung using FXN / Frataxin antibody (16-775) at dilution of 1:100 (40x lens).
5 / 5
Immunohistochemistry of paraffin-embedded rat pancreas using FXN / Frataxin antibody (16-775) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human mammary cancer using FXN / Frataxin antibody (16-775) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human colon using FXN / Frataxin antibody (16-775) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human lung cancer using FXN / Frataxin antibody (16-775) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat lung using FXN / Frataxin antibody (16-775) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat pancreas using FXN / Frataxin antibody (16-775) at dilution of 1:100 (40x lens).

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PSI-16-775-50uL50uL£433.00
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Further Information

Additional Names:
Frataxin, mitochondrial, Friedreich ataxia protein, Fxn, Frataxin intermediate form, i-FXN, Frataxin(56-210), m56-FXN, Frataxin(78-210), d-FXN, m78-FXN, Frataxin mature form, Frataxin(81-210), m81-FXN, FXN, FRDA, X25
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:200

IF: 1:50 - 1:200
Background:
This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 42-210 of human FXN (NP_000135.2).
NCBI Gene ID #:
2395
NCBI Official Name:
Frataxin, mitochondrial
NCBI Official Symbol:
FXN
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Affinity purification
Research Area:
Signal Transduction
Swissprot #:
Q16595
User NOte:
Optimal dilutions for each application to be determined by the researcher.