ProSci

RNF7 Antibody

Product Code:
 
PSI-22-847
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Shipping:
 
Blue Ice or RT
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunofluorescence analysis of MCF-7 cells using RNF7 antibody (22-847). Blue: DAPI for nuclear staining.
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Immunofluorescence analysis of MCF-7 cells using RNF7 antibody (22-847). Blue: DAPI for nuclear staining.

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PSI-22-847-50uL50uL£433.00
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Further Information

Additional Names:
RNF7, zinc RING finger protein SAG, sensitive to apoptosis, regulator of cullins 2, OTTHUMP00000180645, SAG, ROC2, CKBBP1, ring finger protein 7, RNF7, RBX2
Application Note:
WB: 1:500 - 1:2000

IF: 1:20 - 1:50
Background:
The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-113 of human RNF7 (NP_055060.1).
NCBI Gene ID #:
9616
NCBI Official Name:
ring finger protein 7
NCBI Official Symbol:
RNF7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Affinity purification
Research Area:
Apoptosis, Cell Cycle
Swissprot #:
Q9UBF6
User NOte:
Optimal dilutions for each application to be determined by the researcher.