ProSci

IFN-beta Recombinant Protein (Animal Free)

Product Code:
 
PSI-40-748
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Shipping:
 
Blue Ice or room temp
Storage:
 
The recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing the recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
 

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PSI-40-748-5ug5ug£324.00
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This product comes from: United States.
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Further Information

Additional Names:
Leukocyte interferon, B cell interferon, Type I interferon
Background:
Proteins of this family play an important role in inducing non-specific resistance against a broad range of viral infections. They also affect cell proliferation and modulate immune responses. Produced by peripheral blood leukocytes and lymphoblastoid cells, IFN-α is an acid-stable molecule that signals through IFN-α/βR, which is also used by IFN-β. Both IFNs have similar anti-viral activity and regulate expression of MHC class I antigens. IFN-α contains four highly conserved cysteine residues that form two disulfide bonds, one of which is necessary for biological activity. Recombinant Human IFN-β is a 20.0 kDa protein containing 166 amino acid residues.
Biological Activity:
Determined by its ability to stimulate the proliferation of human TF-1 cells. The expected ED50 is < 0.25 ng/ml, corresponding to a specific activity of < 4 x 106 units/mg.
NCBI Gene ID #:
3456
NCBI Official Name:
interferon beta 1
NCBI Official Symbol:
IFNB1
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Purity:
> 95% by SDS-PAGE gel and HPLC analyses.
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P01574

Documents