RevMab Biosciences

anti-PD-1 (human) Rabbit Monoclonal (RM309)

Product Code:
 
REV-31-1195-00
Product Group:
 
Primary Antibodies
Supplier:
 
RevMab Biosciences
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Recombinant Antibody
Antibody Clone:
 
RM309
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
Blue Ice
Storage:
 
+4°C
1 / 1
Immunohistochemical staining of formalin fixed and paraffin embedded human tonsil tissue section using anti-PD-1 rabbit monoclonal antibody (Clone RM309) at a 1:500 dilution.
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Immunohistochemical staining of formalin fixed and paraffin embedded human tonsil tissue section using anti-PD-1 rabbit monoclonal antibody (Clone RM309) at a 1:500 dilution.

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REV-31-1195-00-R100100 ul£497.00
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This product comes from: Switzerland.
Typical lead time: 14-21 working days.
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Further Information

Alternate Names/Synonyms:
CD279; Programmed Cell Death Protein 1
Concentration:
N/A
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Handling Advice:
Avoid freeze/thaw cycles.
Immunogen:
A peptide corresponding to the N-terminus of human PD-1.
Long Description:
Recombinant Antibody. This antibody reacts to human PD-1 (Programmed cell death protein 1) (CD279). Applications: WB, IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. Programmed Death 1 (PD-1) is a member of the CD28/CTLA-4 family of T cell regulators, expressed as a co-receptor on the surface of activated T cells, B cells and macrophages. Several studies have suggested that the PD-1/PD-L1 signaling pathway may be linked to antitumor immunity, as PD-L1 has been shown to induce apoptosis of activated T cells or inhibit activity of cytotoxic T cells. In comparison to CD10 and Bcl-6, PD-1 is expressed by fewer B cells and has therefore been considered a more specific and useful diagnostic marker for angioimmunoblastic T cell lymphoma. Therapies targeted toward the PD-1 receptor have shown remarkable clinical responses in patients with various types of cancer, including non-small-cell lung cancer, melanoma and renal-cell cancer.
NCBI, Uniprot Number:
Q15116
Package Type:
Vial
Product Description:
Programmed Death 1 (PD-1) is a member of the CD28/CTLA-4 family of T cell regulators, expressed as a co-receptor on the surface of activated T cells, B cells and macrophages. Several studies have suggested that the PD-1/PD-L1 signaling pathway may be linked to antitumor immunity, as PD-L1 has been shown to induce apoptosis of activated T cells or inhibit activity of cytotoxic T cells. In comparison to CD10 and Bcl-6, PD-1 is expressed by fewer B cells and has therefore been considered a more specific and useful diagnostic marker for angioimmunoblastic T cell lymphoma. Therapies targeted toward the PD-1 receptor have shown remarkable clinical responses in patients with various types of cancer, including non-small-cell lung cancer, melanoma and renal-cell cancer.
Purity:
Protein A purified.
Source / Host:
Rabbit
Specificity:
This antibody reacts to human PD-1 (Programmed cell death protein 1) (CD279).
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.