RevMab Biosciences

anti-CD21 (human) Rabbit Monoclonal (RM372)

Product Code:
 
REV-31-1258-00
Product Group:
 
Primary Antibodies
Supplier:
 
RevMab Biosciences
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Recombinant Antibody
Antibody Clone:
 
RM372
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
Blue Ice
Storage:
 
+4°C
1 / 1
Immunohistochemical staining of formalin fixed and paraffin embedded human tonsil tissue section using anti-CD21 rabbit monoclonal antibody (Clone RM372) at a 1:1000 dilution.
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Immunohistochemical staining of formalin fixed and paraffin embedded human tonsil tissue section using anti-CD21 rabbit monoclonal antibody (Clone RM372) at a 1:1000 dilution.

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REV-31-1258-00-R100100 ul£455.00
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This product comes from: Switzerland.
Typical lead time: 14-21 working days.
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Further Information

Alternate Names/Synonyms:
Complement Receptor Type 2; Cr2; Complement C3d Receptor; Epstein-Barr Virus Receptor; EBV Receptor
Concentration:
N/A
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Handling Advice:
Avoid freeze/thaw cycles.
Immunogen:
A peptide corresponding to the C-terminus of human CD21 (Complement receptor type 2).
Long Description:
Recombinant Antibody. This antibody reacts to human CD21 (Complement receptor type 2). Applications: WB, IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. CD21 (Complement Receptor 2; CR2; EBV receptor) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to follicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation. Genetic variations in the CD21 gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9).
NCBI, Uniprot Number:
P20023
Package Type:
Vial
Product Description:
CD21 (Complement Receptor 2; CR2; EBV receptor) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to follicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation. Genetic variations in the CD21 gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9).
Purity:
Protein A purified.
Source / Host:
Rabbit
Specificity:
This antibody reacts to human CD21 (Complement receptor type 2).
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.