ProSci

ACE-2 Recombinant Protein

Product Code:
 
PSI-10-014
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Virus
Storage:
 
Store in working aliquots at -20˚C. Avoid freeze/thaw cycles.
 

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PSI-10-014-0.1mg0.1mg£729.00
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Further Information

Additional Names:
Angiotensin-Converting Enzyme 2, ACE-Related Carboxypeptidase, Angiotensin-Converting Enzyme Homolog, ACEH, Metalloprotease MPROT15, ACE2
Background:
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family which includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase and converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be highly expressed in testis, kidney, heart, colon, small intestine and ovary at moderate levels. ACE2 is not inhibited by the classical ACE inhibitors, captopril and lisinopril and may play an important role in regulating the heart function.
Biological Activity:
Human ACE2 protein can bind with SARS-CoV-2 Spike protein (RBD) in functional ELISA assay.
Buffer:
20mM Tris, 300mM NaCl, 1mM ZnCl2, 10% Glycerol, pH 7.4.
Concentration:
batch dependent
Fusion Tag:
His Tag
NCBI Gene ID #:
59272
NCBI Official Name:
angiotensin-converting enzyme 2
NCBI Official Symbol:
ACE2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
Mol Mass: 84.63kD; AP Mol Mass: 103kD
Protein Accession #:
Q9BYF1
Purity:
>95% as determined by reducing SDS-PAGE.
Recombinant Protein Sequence:
#N/A
Source:
HEK293 cells

Documents