SARS-CoV-2 (COVID-19) NSP8 Recombinant Protein

Product Code:

PSI-10-415

Product Group:

Recombinant Proteins

Supplier:

ProSci

Host Type:

E.coli

Regulatory Status:

RUO

Shipping:

blue ice or RT

Storage:

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 ˚C for one week. Store at -20 to -80 ˚C for twelve months from the date of receipt.

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Code	Size	Price

PSI-10-415-0.1mg

0.1mg

£657.00

Quantity:

Prices exclude any Taxes / VAT

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Further Information

Additional Names:

SARS-CoV 2 nsp8

Application Note:

Immunogen

Background:

Cleavage by the viral main protease, 3CLpro results in generating the nsp8 protein, The nsp8 protein has been shown to associate with several other nsps and to colocalize with these nsps in cytoplasmic complexes that are important for viral RNA synthesis. It forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers. Nsp8 was shown to have RNA-dependent RNA polymerase (RdRp) activity that could be involved in producing primers utilized by nsp12 which is normally accepted to be the RdRp for SARS-CoV.

Buffer:

Supplied as lyophilized from PBS, pH 7.5. Please reconstitute the protein with ddH2O to the concentration with 1mg/ml.

Fusion Tag:

N-His Tag

Physical State:

Lyophilized

Predicted Molecular Weight:

24.18kDa

Protein Accession #:

YP_009725304.1

Purity:

>85% as determined by SDS-PAGE quantitative densitometry by Coomassie Blue Staining.

Recombinant Protein Sequence:

#N/A

Source:

E. coli

Documents

Datasheet