ProSci

GASP-1 Recombinant Protein

Product Code:
 
PSI-40-591
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Host Type:
 
Hamster
Regulatory Status:
 
RUO
Target Species:
 
Human
Shipping:
 
blue ice or RT
Storage:
 
The lyophilized GASP-1 recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted GASP-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing GASP-1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
 

No additional charges, what you see is what you pay! *

CodeSizePrice
PSI-40-591-0.005mg0.005mg£300.00
Quantity:
PSI-40-591-0.025mg0.025mg£428.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 14-21 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Additional Names:
GASP, GASP1, GASP-1, GASP, KIAA0443, G-protein coupled receptor-associated sorting protein 1
Background:
Growth and differentiation factor-associated serum protein-1 (GASP-1) is a secreted inhibitory TGF-β binding protein that contains multiple protease inhibitor structural domains. It is expressed primarily in the ovary, testis, and brain, and can act as a potent soluble inhibitor of myostatin and GDF-11, but not Activin-A. The GASP-1 gene encodes a 571 amino acid protein that contains a 29 amino acid secretion signal sequence, and multiple identifiable structural features, including a WAP domain, a follistatin/Kazal domain, an immunoglobulin domain, two tandem Kunitz domains, and a netrin domain. Recombinant human GASP-1 is a 542 amino acid protein that migrates at an apparent molecular weight of approximately 55-66 kDa by SDS-PAGE analysis under non-reducing conditions.
Biological Activity:
Determined by its ability to inhibit human Myostatin (GDF-8) activity in MCP-11 cells. The ED50 for this effect is 0.0025-0.0040 μg/mL in the presence of 5 ng/mL of human Myostatin (GDF-8).
NCBI Gene ID #:
9737
NCBI Official Name:
G protein-coupled receptor associated sorting protein 1
NCBI Official Symbol:
GPRASP1
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_001092880.1
Protein GI Number:
150378489
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Recombinant Protein Sequence:
#N/A
Source:
CHO cells
Swissprot #:
Q5JY77

Documents