ProSci

IL-1 Rrp2 / IL-1 R6 Recombinant Protein

Product Code:
 
PSI-11-170
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Host Type:
 
Human
Regulatory Status:
 
RUO
Target Species:
 
Cynomolgus Monkey
Application:
 
Western Blot (WB)
Shipping:
 
blue ice or RT
Storage:
 
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
 

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PSI-11-170-0.1mg0.1mg£657.00
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Further Information

Additional Names:
IL-1 R6,IL-1 Rrp2,IL1RL2,IL-1RL2,IL1Rrp2,IL-1Rrp2,IL1RRP2,IL-36R
Application Note:
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 37.9 kDa. The protein migrates as 50-66 kDa under reducing (R) condition (SDS-PAGE) due to Glycosylation.
Background:
The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1?RI (IL-1 R1), IL-1?RII (IL-1?R2), IL-1?RAcP (IL-1?R3), ST2 (T1/IL-1?R4), IL-18?Ra (IL-1?Rrp/IL-1?R5), IL-1?Rrp2 (IL-1?RL2/IL-1?R6), IL-18?Rb (AcPL/IL-1?R7), IL-1RAPL-1 (TIGIRR-2/IL-1?R8), and TIGIRR-1 (IL-1?R9). All family members possess three immunoglobulin (Ig)-like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor signaling) domain that is also conserved in the Toll-like receptor family. Related proteins, SIGIRR (single Ig domain-containing IL-1 R-related molecule) and IL-18BP, differ from the other members by having only one Ig domain.
Background References:
  • Boraschi D., et al.?2013, Semin Immunol., 25(6), 394-407.
  • Lovenberg TW., et al.?2013, Semin Immunol., 25(6), 394-407.
  • Debets R., et al.?2001, J Immunol., 167(3), 1440-6.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
Physical State:
Lyophilized
Predicted Molecular Weight:
37.9 kDa
Protein Accession #:
EHH61702.1
Purity:
>90% as determined by SDS-PAGE.
Recombinant Protein Sequence:
#N/A
Source:
HEK293 cells

Documents