ProSci

ANGPTL7 / CDT6 Recombinant Protein

Product Code:
 
PSI-11-508
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Host Type:
 
Human
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Shipping:
 
blue ice or RT
Storage:
 
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
 

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PSI-11-508-0.1mg0.1mg£729.00
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Further Information

Additional Names:
ANGPTL7,CDT6
Application Note:
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 64.1 kDa. The protein migrates as 60 kDa and 76 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Background:
Angiopoietin-like 7 (ANGPTL7) is also known as Corneal-Derived Transcript 6 (CDT6), and is a secreted glycoprotein that is structurally related to the angiopoietins. It is expressed in the corneal stroma, trabecular meshwork, and sclera and is elevated in glaucoma aqueous humor. Recently, ANGPTL proteins, including ANGPTL-2, -3, -4, -5 and -7, are identified as growth factors in combination with SCF, Thrombopoietin, IGF-II and FGF acidic that enhance the expansion and engraftment of human and mouse hematopoietic stem cells.
Background References:
  • Peek R., et al., 1998, Invest. Opthalmol. Visual Sci. 39 (10): 1782-1788.
  • Peek R., et al., 2002, J. Biol. Chem. 277 (1): 686-693.
  • Kuchtey, J. et al., 2008, Invest. Opthalmol. Visual Sci. 49 (8): 3438-3448.
Buffer:
Tris?with?Glycine,?Arginine?and?NaCl,?pH7.5
Fusion Tag:
Mouse IgG Fc Tag
NCBI Gene ID #:
10218
NCBI Official Name:
angiopoietin like 7
NCBI Official Symbol:
ANGPTL7
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
64.1 kDa
Protein Accession #:
NP_066969.1
Purity:
>90% as determined by SDS-PAGE.
Recombinant Protein Sequence:
#N/A
Source:
HEK293 cells
Swissprot #:
O43827

Documents