ProSci

SLAMF1 / SLAM / CD150 Recombinant Protein

Product Code:
 
PSI-11-493
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Host Type:
 
Human
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Shipping:
 
blue ice or RT
Storage:
 
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
 

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PSI-11-493-0.1mg0.1mg£626.00
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Further Information

Additional Names:
SLAMF1,CD150,CDw150,SLAM,IPO-3
Application Note:
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.2 kDa. The protein migrates as 42-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Background:
Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family, also known as CD150, is the prototypic member of the SLAM subfamily of the CD2 protein family.SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. SLAMF1-induced signal-transduction events in T-lymphocytes are different from those in B-cells.?The type I transmembrane glycoprotein Signaling Lymphocytic Activation Molecule (SLAM).
Background References:
  • Cannons JLt, et al., 2011, Annu Rev Immunol., 29, 665-705.
  • Jordan MA, et al., 2011, J Immunol., 186(7), 3953-65.
  • Berger SB, et al., 2010, Nat Immunol., 11(10), 920-7.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
6504
NCBI Official Name:
signaling lymphocytic activation molecule family member 1
NCBI Official Symbol:
SLAMF1
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
26.2 kDa
Protein Accession #:
NP_003028.1
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
#N/A
Source:
HEK293 cells
Swissprot #:
Q13291

Documents