ProSci

B7-H5 / Gi24 / VISTA Recombinant Protein

Product Code:
 
PSI-11-516
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Host Type:
 
Human
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Shipping:
 
blue ice or RT
Storage:
 
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
 

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PSI-11-516-0.1mg0.1mg£657.00
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Further Information

Additional Names:
B7-H5,SISP1,Gi24,VISTA
Application Note:
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 45.0 kDa. The protein migrates as 55-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Background:
Platelet receptor Gi24, also known as B7-H5 and stress-induced secreted protein-1 (Sisp-1), is a protein that in humans is encoded by the C10orf54 gene, which contains 1 Ig-like (immunoglobulin-like) domain. As for C10orf54 gene, C10orf54 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state on ESCs. Human C10orf54 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.
Background References:
  • Sakr M.A., et al., 2010, Cancer Sci. 101:2368-2374.
  • Mayya V., et al ., 2009, Sci. Signal. 2:RA46-RA46.
Buffer:
50 mM Tris, 100 mM Glycine, pH7.5
Fusion Tag:
Mouse IgG Fc Tag
NCBI Gene ID #:
64115
NCBI Official Name:
V-set immunoregulatory receptor
NCBI Official Symbol:
VSIR
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
45.0 kDa
Protein Accession #:
AAH20568.1
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
#N/A
Source:
HEK293 cells
Swissprot #:
Q9H7M9

Documents