ProSci

DLL3 Recombinant Protein

Product Code:
 
PSI-11-467
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Host Type:
 
Human
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Shipping:
 
blue ice or RT
Storage:
 
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
 

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PSI-11-467-0.1mg0.1mg£729.00
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Further Information

Additional Names:
Delta3,delta-like 3 (Drosophila),delta-like protein 3,DLL3,Pudgy,SCDO1,SCDO1delta3
Application Note:
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 75.0 kDa. The protein migrates as 60-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Background:
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands.May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. DLL3 protein is expressed on the surface of tumor cells but not in normal adult tissues.
Background References:
  • Tanaka K., et?al. 2018, Lung Cancer., 115, 116-120.
  • Laura R. Saunders., et?al. 2015, Sci Transl Med., 26, 7(302).
  • Zhang J., et?al. 2017, Oncol Lett., 13(6), 4533-4539.
Buffer:
Tris?with?Glycine,?Arginine?and?NaCl,?pH7.5
Fusion Tag:
Fc Tag
NCBI Gene ID #:
10683
NCBI Official Name:
delta like canonical Notch ligand 3
NCBI Official Symbol:
DLL3
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
75.0 kDa
Protein Accession #:
NP_058637.1
Purity:
>90% as determined by SDS-PAGE.
Recombinant Protein Sequence:
#N/A
Source:
HEK293 cells
Swissprot #:
Q9NYJ7

Documents