ProSci

Glypican 1 / GPC1 Recombinant Protein

Product Code:
 
PSI-11-327
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Host Type:
 
Human
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Shipping:
 
blue ice or RT
Storage:
 
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
 

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PSI-11-327-0.1mg0.1mg£729.00
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Further Information

Additional Names:
Glypican 1,GPC1
Application Note:
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 58.0 kDa. The protein migrates as 60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Background:
Glypican 1 has been shown to interact with SLIT2. This protein is involved in the misfolding of normal prion proteins in the cell membrane to the infectious prion form. Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.
Background References:
  • Vermeesch JR, et al. 1995. Genomics. 25:327-9.
  • Ronca F, et al. 2001. J Biol Chem. 276(31):29141-7.
  • Taylor DR, et al. 2009. PLoS Pathog. 5(11):e1000666.
Buffer:
50 mM Tris, 150 mM NaCl, pH7.5
Fusion Tag:
His Tag
NCBI Gene ID #:
2817
NCBI Official Name:
glypican 1
NCBI Official Symbol:
GPC1
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
58.0 kDa
Protein Accession #:
NP_002072.2
Purity:
>85% as determined by SDS-PAGE.
Recombinant Protein Sequence:
#N/A
Source:
HEK293 cells
Swissprot #:
P35052

Documents