ProSci

PLGF / PGF (19-149) Recombinant Protein

Product Code:
 
PSI-11-158
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Host Type:
 
Human
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Shipping:
 
blue ice or RT
Storage:
 
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
 

No additional charges, what you see is what you pay! *

CodeSizePrice
PSI-11-158-0.02mg0.02mg£657.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 14-21 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Additional Names:
PGF,PLGF,PlGF,PGFL,SHGC-10760
Application Note:
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 41.2 kDa. The protein migrates as 50-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Background:
Placental growth factor (PGF) is also known as vascular endothelial growth factor-related protein, PLGF and PlGF2, is a member of the VEGF (vascular endothelial growth factor) sub-family - a key molecule in angiogenesis and vasculogenesis, in particular during embryogenesis. The main source of PGF during pregnancy is the placental trophoblast. PGF is also expressed in many other tissues, including the villous trophoblast. PGF is actived in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. PlGF2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.
Background References:
  • Maglione D., et al., 1993, Oncogene 8 (4): 925?31.
  • Khalil A., et al., 2008, PLoS ONE 3 (7): e2766.
  • Khurana R., et al., 2005, Circulation 111 (21): 2828?2836.
  • Rolny C., et al., 2011, Cancer Cell 19:31-44.
Buffer:
PBS, pH7.4
Fusion Tag:
Fc Tag
NCBI Gene ID #:
5228
NCBI Official Name:
placentalgrowthfactor
NCBI Official Symbol:
PGF
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
41.2 kDa
Protein Accession #:
NP_001193941.1
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
#N/A
Source:
HEK293 cells
Swissprot #:
P49763

Documents