ProSci

EGF Recombinant Protein

Product Code:
 
PSI-11-373
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Host Type:
 
Human
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Shipping:
 
blue ice or RT
Storage:
 
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
 

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CodeSizePrice
PSI-11-373-0.1mg0.1mg£657.00
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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Additional Names:
EGF,URG,HOMG4
Application Note:
This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 32.5 kDa. The protein migrates as 35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Background:
Human epidermal growth factor (EGF) is also known as HOMG4 and? URG,and is a growth factor that plays an important role in the regulation of cell growth, proliferation, and differentiation by binding to its receptor EGFR. Epidermal growth factor can be found in human platelets, macrophages, urine, saliva, milk, and plasma. EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. All family members contain one or more repeats of the conserved amino acid sequence. The biological effects of salivary EGF include healing of oral and gastroesophageal ulcers, inhibition of gastric acid secretion, stimulation of DNA synthesis as well as mucosal protection from intraluminal injurious factors such as gastric acid, bile acids, pepsin, and trypsin and to physical, chemical and bacterial agents. Because of the increased risk of cancer by EGF, inhibiting it decreases cancer risk.
Background References:
  • Barnham KJ,et al. 1998, Protein Science 7 (8): 1738?49.
  • Cotran, Ramzi S.,et al. 2005, Robbins and Cotran pathologic basis of disease.
  • Dreux AC,et al. 2006, Atherosclerosis 186 (1): 38?53.
  • Venturi S,et al.2009, Nutrition and Health 20 (2): 119?134.
Buffer:
Tris?with?Glycine,?Arginine?and?NaCl,?pH7.5
Fusion Tag:
Fc Tag
NCBI Gene ID #:
13645
NCBI Official Name:
epidermal growth factor
NCBI Official Symbol:
Egf
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Predicted Molecular Weight:
32.5 kDa
Protein Accession #:
NP_034243.2
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
#N/A
Source:
HEK293 cells
Swissprot #:
P01132

Documents