ProSci

CD155 / PVR Recombinant Protein

Product Code:
 
PSI-11-539
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Host Type:
 
Human
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Shipping:
 
blue ice or RT
Storage:
 
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
 

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PSI-11-539-0.05mg0.05mg£729.00
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This product comes from: United States.
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Further Information

Additional Names:
PVR,FLJ25946,PVS,CD155,TAGE4,HVED,NECL5
Application Note:
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 61.8 kDa. The protein migrates as 35 kDa and 70-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Background:
CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that is encoded by the PVR gene. CD155 is a Type I transmembrane glycoprotein in the immunoglobulin superfamily. Commonly known as Poliovirus Receptor (PVR) due to its involvement in the cellular poliovirus infection in primates, CD155's normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. The role of CD155 in the immune system is unclear, though it may be involved in intestinal humoral immune responses. Subsequent data has also suggested that CD155 may also be used to positively select MHC-independent T cells in the thymus.
Background References:
  • Zhang P., et al., 2008, Proc. Natl. Acad. Sci., 105 (47): 18284-18289.
  • Maier MK., et al., 2007, European Journal of Immunology, 37 (8): 2214-2225.
  • He Y., et al., 2000, Proc. Natl. Acad. Sci., 97 (1): 79-84.
Buffer:
Tris?with?Glycine,?Arginine?and?NaCl,?pH7.5
Fusion Tag:
Mouse IgG Fc Tag
NCBI Gene ID #:
52118
NCBI Official Name:
poliovirus receptor
NCBI Official Symbol:
Pvr
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Predicted Molecular Weight:
61.8 kDa
Protein Accession #:
NP_081790.1
Purity:
>95% as determined by reduced SDS-PAGE.
Recombinant Protein Sequence:
#N/A
Source:
HEK293 cells

Documents