ProSci

Canine GITR / TNFRSF18 Recombinant Protein

Product Code:
 
PSI-11-362
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Host Type:
 
Human
Regulatory Status:
 
RUO
Target Species:
 
Canine (dog)
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Shipping:
 
blue ice or RT
Storage:
 
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
 

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CodeSizePrice
PSI-11-362-0.1mg0.1mg£729.00
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This product comes from: United States.
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Further Information

Additional Names:
AITR,GITR,TNFRSF18,CD357
Application Note:
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 15.8 kDa. The protein migrates as 20-25 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Background:
Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Background References:
  • Tuyaerts S., et al., 2007, J. Leukoc. Biol. 82:93-105.
  • Chattopadhyay K., et al., 2007, Proc. Natl. Acad. Sci. U.S.A. 104:19452-19457.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
606971
NCBI Official Name:
TNF receptor superfamily member 18
NCBI Official Symbol:
TNFRSF18
NCBI Organism:
Canis lupus familiaris
Physical State:
Lyophilized
Predicted Molecular Weight:
15.8 kDa
Protein Accession #:
NP_001177673.1
Purity:
>90% as determined by SDS-PAGE.
Recombinant Protein Sequence:
#N/A
Source:
HEK293 cells

Documents