ProSci

Rhesus macaque / Complement Factor D / CFD Recombinant Protein

Product Code:
 
PSI-11-370
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Host Type:
 
Human
Regulatory Status:
 
RUO
Target Species:
  • Cynomolgus Monkey
  • Rhesus Macaque
Application:
 
Western Blot (WB)
Shipping:
 
blue ice or RT
Storage:
 
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
 

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PSI-11-370-0.1mg0.1mg£729.00
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Further Information

Additional Names:
CFD,Adipsin,PFD,DF,Complement factor D
Application Note:
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.5 kDa. The protein migrates as 25-27 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Background:
Complement factor D (CFD) is also known as Adipsin, C3 convertase activator, Properdin factor D (PFD), which contains one peptidase S1 domain and belongs to the peptidase S1 family. CFD / Adipsin cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. CFD / Adipsin is a serine protease that stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. Defects in CFD / Adipsin are the cause of complement factor D deficiency which predisposes to invasive meningococcal disease.
Background References:
  • White R.T., et al., 1992, J. Biol. Chem. 267:9210-9213.
  • Johnson D.M.A., et al., 1984, FEBS Lett. 166:347-351.
  • Sprong T., et al., 2006, Blood 107:4865-4870.
Buffer:
50 mM Tris, 150 mM NaCl, pH8.0
Fusion Tag:
His Tag
NCBI Gene ID #:
102136571
NCBI Official Name:
complement factor D
NCBI Official Symbol:
CFD
NCBI Organism:
Macaca fascicularis
Physical State:
Lyophilized
Predicted Molecular Weight:
26.5 kDa
Protein Accession #:
XP_005587397.1
Purity:
>90% as determined by SDS-PAGE.
Recombinant Protein Sequence:
#N/A
Source:
HEK293 cells

Documents