ProSci

IL-36beta Recombinant Protein

Product Code:
 
PSI-40-602
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Host Type:
 
E.coli
Regulatory Status:
 
RUO
Target Species:
 
Human
Shipping:
 
blue ice or RT
Storage:
 
The lyophilized IL-36beta recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted IL-36beta is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing IL-36beta recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
 

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CodeSizePrice
PSI-40-602-0.002mg0.002mg£300.00
Quantity:
PSI-40-602-0.01mg0.01mg£428.00
Quantity:
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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Additional Names:
FIL1, FIL1H, IL1F8, IL1H2, IL-1F8, IL-1H2, IL1-ETA, FIL1-(ETA), FILI-(ETA), Interleukin-36 beta, FIL1 eta, IL-1 eta
Background:
The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-36α (IL-1F6), β (IL-1F8) and γ (IL-1F9). IL-36β is highly expressed in psoriatic plaques, and at lower levels in various other tissues. IL-36β signals through the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells. The interaction of the IL-1Rrp2 receptor with IL-36 ligands induces dendritic cell maturation and activation. IL-36β also functions as an agonist of NF-kappaB, and stimulates the production of pro-inflammatory proteins, including IL-6, IL-8, BD-2, and BD-3. Recombinant human IL-36β is a 17.3 kDa protein containing 154 amino acid residues.
NCBI Gene ID #:
27177
NCBI Official Name:
interleukin 36, beta
NCBI Official Symbol:
IL36B
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_055253.2
Protein GI Number:
20070252
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
Q9NZH7

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