ProSci

Iba1 / AIF-1 Recombinant Protein

Product Code:
 
PSI-11-239
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Host Type:
 
E.coli
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Shipping:
 
blue ice or RT
Storage:
 
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
 

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PSI-11-239-0.1mg0.1mg£626.00
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Further Information

Additional Names:
Iba1,AIF-1,AIF1,G1,IBA1,LCP1
Application Note:
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 18.6 kDa. The protein migrates as 18-20 kDa under reducing (R) condition (SDS-PAGE).
Background:
Allograft inflammatory factor 1 (AIF1), also known as IBA1, daintain and Protein G1, is an actin-binding protein. Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
Background References:
  • Chen X, et al. 2004. Arterioscler Thromb Vasc Biol. 24(7):1217-22.
  • Kelemen SE, et al. 2005. Am J Pathol. 167(2):619-26.
  • Schulze JO, et al. 2008. FEBS J. 275(18):4627-40.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
199
NCBI Official Name:
allograftinflammatoryfactor1
NCBI Official Symbol:
AIF1
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
18.6 kDa
Protein Accession #:
NP_001614.3
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P55008

Documents