ProSci

GDF-5 Recombinant Protein

Product Code:
 
PSI-40-579
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Host Type:
 
E.coli
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Shipping:
 
blue ice or RT
Storage:
 
The lyophilized GDF-5 recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted GDF-5 stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing GDF-5 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
 

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CodeSizePrice
PSI-40-579-0.01mg0.01mg£300.00
Quantity:
PSI-40-579-0.05mg0.05mg£428.00
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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Additional Names:
OS5, LAP4, BDA1C, BMP14, CDMP1, SYM1B, SYNS2, Cartilage-derived morphogenetic protein 1, GDF-5
Background:
GDF-5 is expressed in long bones during embryonic development and postnatally in articular cartilage. Mutations in the GDF-5 gene have been implicated in Grebe Syndrome, which is characterized by short stature, extra digits, short and deformed extremities, and in Hunter-Thompson type dwarfism. The mature and functional form of GDF-5 is a homodimer of two 120 amino-acid polypeptide chain (monomers) linked by a single disulfide bond. Each GDF-5 monomer is expressed as the C-terminal part of a precursor polypeptide, which also contains a 27 amino-acid signal peptide and a 348 amino-acid propeptide. This precursor undergoes intracellular dimerization, and upon secretion it is processed by a furin-type protease. Recombinant murine GDF-5 is a 27.0 kDa homodimeric disulfide-linked protein consisting of two 120 amino acids.
Biological Activity:
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
NCBI Gene ID #:
8200
NCBI Official Name:
growth differentiation factor 5
NCBI Official Symbol:
GDF5
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_000548.1
Protein GI Number:
4503969
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P43026

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