ProSci

Onchocerca volvulus OV16 Recombinant Protein

Product Code:
 
PSI-11-156
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Host Type:
 
E.coli
Regulatory Status:
 
RUO
Target Species:
 
Onchocerca?species
Application:
 
Western Blot (WB)
Shipping:
 
blue ice or RT
Storage:
 
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
 

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CodeSizePrice
PSI-11-156-0.1mg0.1mg£729.00
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This product comes from: United States.
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Further Information

Additional Names:
OV16,OV-16 antigen
Application Note:
This protein carries a GST tag at the N-terminus. The protein has a calculated MW of 46.8 kDa. The protein migrates as 45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Background:
The OV16 antigen, localizes to the hypodermis, cuticle, and uterus of female O. volvulus is regarded as a highly sensitive and specific antigen for detection of IgG4 in people with prior exposure to onchocerciasis. It has an open reading frame that encodes a 152- amino acid polypeptide containing a 16-amino acid putative signal peptide. Enzyme-linked Immunosorbent Assay serological testing of OV-16 antigen is a diagnostic tool for determining effective elimination of the parasite.
Background References:
  • Cama, Vitaliano A., et al., 2018, Am. J. Trop. Med. Hyg., 1-8.
  • Miley, Kristi M., 2017, Graduate Theses and Dissertations., 1-42.
  • E Lobos., at al., 1991, Science, 251:1603-1605.
Buffer:
PBS, pH7.4
Fusion Tag:
GST Tag
Physical State:
Lyophilized
Predicted Molecular Weight:
46.8 kDa
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
#N/A
Source:
E. coli

Documents