ProSci

HGF Recombinant Protein

Product Code:
 
PSI-40-580
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Host Type:
 
Insect
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Shipping:
 
blue ice or RT
Storage:
 
The lyophilized HGF recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted HGF stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing HGF recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
 

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CodeSizePrice
PSI-40-580-0.005mg0.005mg£300.00
Quantity:
PSI-40-580-0.02mg0.02mg£428.00
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This product comes from: United States.
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Further Information

Additional Names:
SF, NK1, NK2, HGF/SF, SF/HGF, C230052L06Rik, Hepatocyte growth factor, Hepatopoietin-A, SF
Background:
HGF is a mesenchymally derived potent mitogen for mature parenchymal hepatocyte cells and acts as a growth factor for a broad spectrum of tissues and cell types. HGF signals through a transmembrane tyrosine kinase receptor known as MET. Activities of HGF include induction of cell proliferation, motility, morphogenesis, inhibition of cell growth, and enhancement of neuron survival. HGF is a crucial mitogen for liver regeneration processes, especially after partial hepatectomy and other liver injuries. Human and murine HGF are cross-reactive. Murine HGF is expressed as a linear 728 amino acid polypeptide precursor glycoprotein. Proteolytic processing of this precursor generates the biologically active form of HGF, which consists of two polypeptide chains (α-chain and β-chain) held by a single disulfide bond resulting in formation of a biologically active heterodimer. The α-chain consists of 463 amino acid residues and four kringle domains. The β-chain consists of 233 amino acid residues.*Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc.
Biological Activity:
Biological activity was determined by the dose-dependent stimulation of the proliferation of mouse IMCD3 cells using a concentration range of 10-20 ng/mL. Endotoxin level is less than 0.1 ng per μg of HGF (1EU/μg).
NCBI Gene ID #:
15234
NCBI Official Name:
hepatocyte growth factor
NCBI Official Symbol:
Hgf
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Protein Accession #:
NP_001276387.1
Protein GI Number:
575501559
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Recombinant Protein Sequence:
#N/A
Source:
(BTI-Tn-5B1-4) High-5 Insect cells
Swissprot #:
Q08048

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