NSJ Bioreagents

XRN1 Antibody

Product Code:
 
NSJ-F53814
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG1, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
1647CT536.85.48
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Aliquot the XRN1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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Western blot testing of human 1) K562 and 2) MCF7 cell lysate with XRN1 antibody at 1:2000. Predicted molecular weight: 194 kDa.
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Western blot testing of human 1) K562 and 2) MCF7 cell lysate with XRN1 antibody at 1:2000. Predicted molecular weight: 194 kDa.

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CodeSizePrice
NSJ-F53814-0.05ML0.05 ml£260.00
Quantity:
NSJ-F53814-0.2ML0.2 ml£502.00
Quantity:
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Further Information

Application Details :
Western blot: 1:1000-2000
Description:
5'-3' Exoribonuclease 1 is a major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS).
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Gene ID #:
54464
Immunogen:
A human recombinant protein corresponding to amino acids 1455-1706 was used as the immunogen for the XRN1 antibody.
Limitation:
This XRN1 antibody is available for research use only.
Purity:
Protein G affinity chromatography
Species Reactivity :
Human
Uniprot #:
Q8IZH2