NSJ Bioreagents

AMACR / p504S Antibody (Prostate Cancer Marker)

Product Code:
 
NSJ-V3237
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG2b, lambda
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
AMACR/1723
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Store the AMACR antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
1 / 3
Western blot testing of human PC3 cell lysate with AMACR antibody. Predicted molecular weight ~43 kDa.
2 / 3
Western blot testing of human kidney lysate with AMACR antibody. Predicted molecular weight ~43 kDa.
3 / 3
SDS-PAGE Analysis of Purified, BSA-Free AMACR Antibody (clone AMACR/1723). Confirmation of Integrity and Purity of the Antibody.
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Western blot testing of human PC3 cell lysate with AMACR antibody. Predicted molecular weight ~43 kDa.
Western blot testing of human kidney lysate with AMACR antibody. Predicted molecular weight ~43 kDa.
SDS-PAGE Analysis of Purified, BSA-Free AMACR Antibody (clone AMACR/1723). Confirmation of Integrity and Purity of the Antibody.

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CodeSizePrice
NSJ-V3237-20UG20 ug£264.00
Quantity:
NSJ-V3237-100UG100 ug£534.00
Quantity:
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Further Information

Application Details :
Western blot: 0.5-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
Application Note:
Optimal dilution of the AMACR antibody should be determined by the researcher.
Description:
AMACR, also known as p504S is an enzyme that is involved in bile acid biosynthesis and beta-oxidation of branched-chain fatty acids. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands.
Format :
Purified
Formulation :
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Immunogen:
A recombinant human protein was used as the immunogen for the AMACR antibody.
Limitation:
This AMACR antibody is available for research use only.
Localization:
Cytoplasmic
Purity:
Protein G affinity chromatography
Species Reactivity :
Human
Uniprot #:
Q9UHK6