PDCD1 Antibody / PD-1 / PD1

Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT

Titering of the recombinant PD1 antibody may be required for optimal performance.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

PDCD1 (Programmed cell death-1 protein), also called PD1 and CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD1 is expressed by few B-cells, so may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma.

Purified

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

A partial length human protein was used as the immunogen for the recombinant PD1 antibody.

This recombinant PD1 antibody is available for research use only.

Cell surface & cytoplasmic

Protein A affinity chromatography

Human

Q15116