NSJ Bioreagents

TAL1 Antibody / T-cell acute lymphocytic leukemia protein 1

Product Code:
 
NSJ-V8107
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG2a, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
TAL1/2707
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
 
Store the TAL1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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SDS-PAGE analysis of purified, BSA-free TAL1 antibody (clone TAL1/2707) as confirmation of integrity and purity.
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SDS-PAGE analysis of purified, BSA-free TAL1 antibody (clone TAL1/2707) as confirmation of integrity and purity.

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CodeSizePrice
NSJ-V8107-20UG20 ug£264.00
Quantity:
NSJ-V8107-100UG100 ug£534.00
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Application Details :
ELISA (order BSA-free format for coating)
Application Note:
Optimal dilution of the antibody should be determined by the researcher.
Description:
Activation of TAL1 characterizes up to 60% of cases of human T cell acute lymphoblastic leukemia, making it the most frequent gain-of-function mutation observed in this disorder. TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. This transcription factor binds as a heterodimer with E2A and HEB/HTF4 to a nucleotide sequence motif termed the E-box. In addition, leukemogenesis is accelerated dramatically by transgenic co-expression of TAL1 and the catalytic subunit of casein kinase IIHLH transcription factors.
Format :
Purified
Formulation :
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Immunogen:
A recombinant human full-length TAL1 protein was used as the immunogen for the TAL1 antibody.
Limitation:
This TAL1 antibody is available for research use only.
Purity:
Protein G affinity chromatography
Species Reactivity :
Human
Uniprot #:
P17542