NSJ Bioreagents

TLE1 Antibody

Product Code:
 
NSJ-V3890
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG2a, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
TLEP1-1
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Store the TLE1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
1 / 2
Western blot testing of human HeLa cell lysate with TLE1 antibody (clone TLEP1-1). Predicted molecular weight ~83 kDa.~
2 / 2
IHC testing of FFPE human endometrial carcinoma with TLE1 antibody (clone TLEP1-1). Required HIER: boil tissue sectio
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Western blot testing of human HeLa cell lysate with TLE1 antibody (clone TLEP1-1). Predicted molecular weight ~83 kDa.~
IHC testing of FFPE human endometrial carcinoma with TLE1 antibody (clone TLEP1-1). Required HIER: boil tissue sectio

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CodeSizePrice
NSJ-V3890-20UG20 ug£264.00
Quantity:
NSJ-V3890-100UG100 ug£534.00
Quantity:
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Further Information

Application Details :
Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
Application Note:
The stated application concentrations are suggested starting points. Titration of the TLE1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG. [UniProt]
Format :
Purified
Formulation :
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Immunogen:
A portion of amino acids 175-338 from the human protein was used as the immunogen for the TLE1 antibody.
Limitation:
This TLE1 antibody is available for research use only.
Localization:
Nuclear
Purity:
Protein G affinity chromatography
Species Reactivity :
Human
Uniprot #:
Q04724