NSJ Bioreagents

GSK3B Antibody

Product Code:
 
NSJ-F51046
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
 
Aliquot the GSK3B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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GSK3B antibody used in western blot to detect GSK3B in 293 cell lysate. Predicted molecular weight ~50 kDa.~
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IHC analysis of FFPE human hepatocarcinoma tissue stained with the GSK3B antibody
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GSK3B antibody used in western blot to detect GSK3B in 293 cell lysate. Predicted molecular weight ~50 kDa.~
IHC analysis of FFPE human hepatocarcinoma tissue stained with the GSK3B antibody

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CodeSizePrice
NSJ-F51046-0.08ML0.08 ml£260.00
Quantity:
NSJ-F51046-0.4ML0.4 ml£502.00
Quantity:
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Further Information

Application Details :
Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
Application Note:
Titration of the GSK3B antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
GSK3B is a constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC, AXIN1, DPYSL2/CRMP2, JUN, NFATC1/NFATC, MAPT/TAU and MACF1. May also mediate the development of insulin resistance by regulating activation of transcription factors. [UniProt]
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 4-34 from the human protein was used as the immunogen for this GSK3B antibody.
Limitation:
This GSK3B antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Species Reactivity (Predicted):
Mouse, Rat
Uniprot #:
P49841