NSJ Bioreagents

DUSP6 Antibody

Product Code:
 
NSJ-F45736
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Aliquot the DUSP6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
1 / 3
DUSP6 antibody western blot analysis in CEM lysate. Predicted molecular weight 42/26 kDa (isoform 1/2).
2 / 3
DUSP6 antibody western blot analysis in mouse stomach tissue lysate. Predicted molecular weight 42/26 kDa (isoform 1/2).
3 / 3
Western blot analysis of DUSP6 antibody and 293 cell lysate either nontransfected (Lane 1) or transiently transfected (2) with the DUSP6 gene.
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DUSP6 antibody western blot analysis in CEM lysate. Predicted molecular weight 42/26 kDa (isoform 1/2).
DUSP6 antibody western blot analysis in mouse stomach tissue lysate. Predicted molecular weight 42/26 kDa (isoform 1/2).
Western blot analysis of DUSP6 antibody and 293 cell lysate either nontransfected (Lane 1) or transiently transfected (2) with the DUSP6 gene.

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CodeSizePrice
NSJ-F45736-0.08ML0.08 ml£260.00
Quantity:
NSJ-F45736-0.4ML0.4 ml£502.00
Quantity:
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This product comes from: United States.
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Further Information

Application Details :
Western blot: 1:1000
Application Note:
Titration of the DUSP6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene.
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 59-88 from the human protein was used as the immunogen for this DUSP6 antibody.
Limitation:
This DUSP6 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse
Species Reactivity (Predicted):
Bovine
Uniprot #:
Q16828