NSJ Bioreagents

GCLC Antibody

Product Code:
 
NSJ-F46551
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Aliquot the GCLC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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GCLC antibody western blot analysis in mouse bladder tissue lysate~
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GCLC antibody western blot analysis in NCI-H292 lysate
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GCLC antibody western blot analysis in mouse bladder tissue lysate~
GCLC antibody western blot analysis in NCI-H292 lysate

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CodeSizePrice
NSJ-F46551-0.08ML0.08 ml£260.00
Quantity:
NSJ-F46551-0.4ML0.4 ml£502.00
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Application Details :
Western blot: 1:1000
Application Note:
Titration of the GCLC antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 286-315 from the human protein was used as the immunogen for this GCLC antibody.
Limitation:
This GCLC antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse
Species Reactivity (Predicted):
Rat
Uniprot #:
P48506