NSJ Bioreagents

APLP1 Antibody (C-Terminal Region)

Product Code:
 
NSJ-F54145
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Aliquot the APLP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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Western blot testing of human 1) U-251 MG and 2) U-87 MG cell lysate with APLP1 antibody at 1:2000. Expected molecular weight: 76 kDa (unmodified), ~86 kDa (soluble/glycosylated form), 92~95 kDa (mature form).
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Western blot testing of human 1) U-251 MG and 2) U-87 MG cell lysate with APLP1 antibody at 1:2000. Expected molecular weight: 76 kDa (unmodified), ~86 kDa (soluble/glycosylated form), 92~95 kDa (mature form).

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CodeSizePrice
NSJ-F54145-0.05ML0.05 ml£260.00
Quantity:
NSJ-F54145-0.2ML0.2 ml£502.00
Quantity:
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Further Information

Application Details :
WB: 1:1000-1:2000
Application Note:
The stated application concentrations are suggested starting points. Titration of the APLP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Amyloid-like protein 1 may play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I.
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 505-539 from human Amyloid-like protein 1 was used as the immunogen for the APLP1 antibody.
Limitation:
This APLP1 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
P51693