TargetMol

TC ASK 10

Product Code:
 
TAR-T13099
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13099-1mg1mg£142.00
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TAR-T13099-5mg5mg£227.00
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TAR-T13099-1mL1 mL * 10 mM (in DMSO)£253.00
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TAR-T13099-10mg10mg£308.00
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TAR-T13099-25mg25mg£470.00
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TAR-T13099-50mg50mg£653.00
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TAR-T13099-100mg100mg£863.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
TC ASK 10 is a potent, selective and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1,IC50 = 14 nM). The IC50 value for ASK2 is 0.51 μM.
CAS:
1005775-56-3
Formula:
C21H23Cl2N5O
Molecular Weight:
432.35
Pathway:
Apoptosis; MAPK
Purity:
0.98
SMILES:
Cl.Cl.CC(C)(C)c1ccc(cc1)C(=O)Nc1cn2cc(ccc2n1)-n1ccnc1
Target:
ASK; MAPK

Documents

References

1. Terao Y, et al. Design and biological evaluation of imidazo[1,2-a]pyridines as novel and potent ASK1 inhibitors. Bioorg Med Chem Lett. 2012 Dec 15;22(24):7326-9.