TargetMol

LSZ-102

Product Code:
 
TAR-T15788
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15788-1mg1mg£136.00
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TAR-T15788-5mg5mg£229.00
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TAR-T15788-1mL1 mL * 10 mM (in DMSO)£230.00
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TAR-T15788-10mg10mg£326.00
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TAR-T15788-25mg25mg£503.00
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TAR-T15788-50mg50mg£651.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
LSZ-102 is an effective and selective degrader of estrogen receptor (IC50 = 0.2 nM) and can be used in studies about ERα positive breast cancer.
CAS:
2135600-76-7
Formula:
C25H17F3O4S
Molecular Weight:
470.46
Pathway:
Endocrinology/Hormones
Purity:
0.9784
SMILES:
CC(F)(F)c1cc(F)ccc1-c1sc2cc(O)ccc2c1Oc1ccc(C=CC(O)=O)cc1
Target:
Estrogen Receptor/ERR

Documents

References

1. Tria GS, et al. Discovery of LSZ102, a Potent, Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer. J Med Chem. 2018 Apr 12;61(7):2837-2864.