TargetMol

S18-000003

Product Code:
 
TAR-T16832
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16832-1mg1mg£140.00
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TAR-T16832-5mg5mg£242.00
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TAR-T16832-1mL1 mL * 10 mM (in DMSO)£266.00
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TAR-T16832-10mg10mg£349.00
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TAR-T16832-25mg25mg£544.00
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TAR-T16832-50mg50mg£747.00
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TAR-T16832-100mg100mg£1,002.00
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TAR-T16832-500mg500mg£1,942.00
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This product comes from: United States.
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Further Information

Bioactivity:
S18-000003 is an effective orally bioavailable retinoic acid receptor-related orphan receptor-gamma-t inhibitor (IC50: 29 nM). S18-000003 inhibits IL-17 production.
CAS:
2068119-11-7
Formula:
C26H25F3N2O4S
Molecular Weight:
518.55
Pathway:
Metabolism
Purity:
0.9991
SMILES:
CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(c(F)c2)C(C)(C)C(=O)Nc2ccc(F)cc2F)cc1
Target:
ROR

References

1. Sasaki Y, et al. Discovery of a potent orally bioavailable retinoic acid receptor-related orphan receptor-gamma-t (ROR?t) inhibitor, S18-000003. Bioorg Med Chem Lett. 2018 Dec 1;28(22):3549-3553.