TargetMol

SMCC-DM1

Product Code:
 
TAR-T16899
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16899-1mg1mg£148.00
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Quantity:
TAR-T16899-5mg5mg£189.00
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Quantity:
TAR-T16899-10mg10mg£291.00
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TAR-T16899-25mg25mg£446.00
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Quantity:
TAR-T16899-50mg50mg£623.00
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Quantity:
TAR-T16899-100mg100mg£855.00
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Quantity:
TAR-T16899-200mg200mg£1,131.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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  • Further Information
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Further Information

Bioactivity:
SMCC-DM1 (DM1-SMCC) is a drug-linker conjugate which composed of a potent microtubule-disrupting agent DM1 and a linker SMCC to make antibody-drug conjugate (ADC).
CAS:
1228105-51-8
Formula:
C51H66ClN5O16S
Molecular Weight:
1072.62
Purity:
0.9925
SMILES:
CO[C@@H]1C=C/C=C(C)Cc2cc(OC)c(Cl)c(c2)N(C)C(=O)C[C@H](OC(=O)[C@H](C)N(C)C(=O)CCSC2CC(=O)N(CC3CCC(CC3)C(=O)ON3C(=O)CCC3=O)C2=O)[C@]2(C)O[C@H]2[C@H](C)[C@@H]2C[C@@]1(O)NC(=O)O2

Documents

References

1. Shao S, et al. Site-specific and hydrophilic ADCs through disulfide-bridged linker and branched PEG. Bioorg Med Chem Lett. 2018 May 1;28(8):1363-1370.