TargetMol

Fluoroglutamine (2S,4R)

Product Code:
 
TAR-T31824
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T31824-10mg10mgEnquire
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TAR-T31824-1mg1mgEnquire
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  • Further Information
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Further Information

Bioactivity:
Fluoroglutamine (2S,4R) is a Glutamine analog, not metabolized in the TCA cycle, but it can be incorporated into proteins and peptides. Fluoroglutamine (2S,4R) can be used as assess transporter (ASCT2) activity or protein synthesis rate.
CAS:
238418-71-8
Formula:
C5H9FN2O3
Molecular Weight:
164.136
Purity:
0.98
SMILES:
N[C@@H](C[C@@H](F)C(N)=O)C(O)=O

Documents

References

1. Ploessl K, Wang L, Lieberman BP, Qu W, Kung HF. Comparative evaluation of 18F-labeled glutamic acid and glutamine as tumor metabolic imaging agents. J Nucl Med. 2012 Oct;53(10):1616-24. doi: 10.2967/jnumed.111.101279. Epub 2012 Aug 30. PubMed PMID: 22935578. 2. Cooper AJ, Krasnikov BF, Pinto JT, Kung HF, Li J, Ploessl K. Comparative enzymology of (2S,4R)4-fluoroglutamine and (2S,4R)4-fluoroglutamate. Comp Biochem Physiol B Biochem Mol Biol. 2012 Sep;163(1):108-20. doi: 10.1016/j.cbpb.2012.05.010. Epub 2012 May 19. PubMed PMID: 22613816; PubMed Central PMCID: PMC3389287.