TargetMol

Praeruptorin A

Product Code:
 
TAR-T3777
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3777-1mg1mg£118.00
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TAR-T3777-5mg5mg£174.00
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TAR-T3777-10mg10mg£246.00
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TAR-T3777-25mg25mg£334.00
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TAR-T3777-50mg50mg£468.00
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TAR-T3777-100mg100mg£624.00
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Further Information

Bioactivity:
Praeruptorin A has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca(2+)/calmodulin-CaMKIV-CREB-NFATc1 and/or Ca(2+)/calmodulin-calcineurin-NFATc1 signaling axis.
CAS:
73069-27-9
Formula:
C21H22O7
Molecular Weight:
386.4
Pathway:
Neuroscience; NF-κb
Purity:
0.9965
SMILES:
CC=C(C)C(=O)O[C@H]1[C@@H](OC(C)=O)c2c(OC1(C)C)ccc1ccc(=O)oc21
Target:
CaMK; NF-κB

References

Xu Z1, Wang X, Dai Y, Kong L, et al.(+/-)-Praeruptorin A enantiomers exert distinct relaxant effects on isolated rat aorta rings dependent on endothelium and nitric oxide synthesis.Chem Biol Interact. 2010 Jul 30;186(2):239-46.