TargetMol

TLR7/8/9-IN-1

Product Code:
 
TAR-T39669
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T39669-1mg1mg£129.00
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TAR-T39669-5mg5mg£230.00
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TAR-T39669-1mL1 mL * 10 mM (in DMSO)£309.00
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TAR-T39669-10mg10mg£349.00
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TAR-T39669-25mg25mg£503.00
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TAR-T39669-50mg50mg£703.00
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Quantity:
TAR-T39669-100mg100mg£930.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
TLR7/8/9-IN-1 is a potent inhibitor of Toll-like receptors 7/8/9 (TLR7/8/9) with an IC50 of 43 nM.
CAS:
2180127-82-4
Formula:
C27H37N3O2
Molecular Weight:
435.6
Pathway:
Immunology/Inflammation
Purity:
0.98
SMILES:
CC(C)c1c(-c(cc2)cc(OC)c2OC)[nH]c2c1cc(C1CCN(CCNC)CC1)cc2
Target:
TLR

Documents

References

Mussari CP, et al. Discovery of Potent and Orally Bioavailable Small Molecule Antagonists of Toll-like Receptors 7/8/9 (TLR7/8/9). ACS Med Chem Lett. 2020 Jul 29;11(9):1751-1758.