TargetMol

TH5427

Product Code:
 
TAR-T39785L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T39785L-1mg1mg£217.00
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Quantity:
TAR-T39785L-2mg2mg£273.00
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Quantity:
TAR-T39785L-5mg5mg£382.00
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Quantity:
TAR-T39785L-10mg10mg£534.00
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Quantity:
TAR-T39785L-25mg25mg£814.00
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Quantity:
TAR-T39785L-50mg50mg£1,083.00
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Quantity:
TAR-T39785L-100mg100mg£1,420.00
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Quantity:
TAR-T39785L-500mg500mg£2,785.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
TH5427 is a lead NUDT5 inhibitor(MG assay IC50?=?29?nM).
CAS:
2253744-56-6
Formula:
C20H20Cl2N8O3
Molecular Weight:
491.33
Pathway:
Metabolism
Purity:
0.98
SMILES:
CN(c1c(C(N2C)=O)n(Cc3nnc(-c(cc4)cc(Cl)c4Cl)o3)c(N3CCNCC3)n1)C2=O
Target:
NUDIX hydrolase

References

Page BDG, et al. Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells [published correction appears in Nat Commun. 2019 Nov 1;10(1):5050]. Nat Commun. 2018;9(1):250.