TargetMol

NF-κβ activator 2

Product Code:
 
TAR-T39924
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T39924-1mg1mg£197.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T39924-5mg5mg£389.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T39924-1mL1 mL * 10 mM (in DMSO)£422.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T39924-10mg10mg£544.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T39924-25mg25mg£830.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T39924-50mg50mg£1,099.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T39924-100mg100mg£1,460.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
NF-κβ activator 2 is a potent and orally active NF-κB activator, with an EC 50 of 1.58 μM. NF-κβ activator 2 induces SOD 2 through increasing NF-κB expression and activation. NF-κβ activator 2 can be used for the research of amyotrophic lateral sclerosis (ALS) [1] .
CAS:
2375281-44-8
Formula:
C16H11FN2O3
Molecular Weight:
298.27
Pathway:
NF-κb
Purity:
0.98
SMILES:
OC(c1cccc(-c2cnc(Nc(cccc3)c3F)o2)c1)=O
Target:
NF-κB

Documents

References

Mathew B, et, al. Structure-activity relationship (SAR) studies of N-(3-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine (SRI-22819) as NF-?B activators for the treatment of ALS. Eur J Med Chem. 2020 Oct 22;112952.