TargetMol

MID-1

Product Code:
 
TAR-T8773
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T8773-1mg1mg£132.00
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TAR-T8773-5mg5mg£201.00
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TAR-T8773-1mL1 mL * 10 mM (in DMSO)£219.00
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TAR-T8773-10mg10mg£269.00
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TAR-T8773-25mg25mg£436.00
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TAR-T8773-50mg50mg£610.00
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Quantity:
TAR-T8773-100mg100mg£838.00
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Quantity:
TAR-T8773-500mg500mg£1,613.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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  • Further Information
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Further Information

Bioactivity:
MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction. It disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake
CAS:
312608-54-1
Formula:
C12H11N3O4S
Molecular Weight:
293.3
Pathway:
; Tyrosine Kinase/Adaptors
Purity:
0.9961
SMILES:
CCOc1ccc(cc1)C(=O)Nc1ncc(s1)[N+]([O-])=O
Target:
IGF-1R

Documents

References

Lee H, et, al. MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) Interaction Disruptor Sensitizes Insulin Signaling in Skeletal Muscle. J Biol Chem. 2016 Dec 23;291(52):26627-26635.