C646

Contact us
TargetMol
Product Code: TAR-T2452
Supplier: TargetMol
CodeSizePrice
TAR-T2452-2mg2mg£103.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2452-1mL1 mL * 10 mM (in DMSO)£121.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2452-5mg5mg£121.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2452-10mg10mg£149.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2452-25mg25mg£236.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2452-50mg50mg£392.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2452-100mg100mg£546.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2452-500mg500mg£1,091.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

1 / 1
❮❯

Documents

Further Information

Bioactivity:
C646, a histone acetyltransferase inhibitor, inhibits p300 (Ki: 400 nM, in a cell-free assay).
CAS:
328968-36-1
Formula:
C24H19N3O6
Molecular Weight:
445.431
Pathway:
Apoptosis; Chromatin/Epigenetic; Autophagy
Purity:
0.9921
SMILES:
CC1=NN(C(=O)C1=C/c1ccc(o1)-c1cc(C)c(C)cc1[N+]([O-])=O)c1ccc(cc1)C(O)=O
Target:
Apoptosis; Epigenetic Reader Domain; Histone Acetyltransferase; Autophagy

References

1. Bowers EM, et al. Chem Biol, 2010, 17(5), 471-482. 2. Santer FR, et al. Mol Cancer Ther, 2011, 10(9), 1644-1655. 3. Crump NT, et al. PNAS, 2011, 108(19), 7814-7819. 4. Marek R, et al. J Neurosci, 2011, 31(20), 7486-7491. 5. Zhu XY, et al. Mol Pain, 2012, 8(84)