TargetMol

Merestinib

Product Code:
 
TAR-T3455
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3455-1mg1mg£107.00
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TAR-T3455-2mg2mg£122.00
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TAR-T3455-5mg5mg£156.00
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TAR-T3455-1mL1 mL * 10 mM (in DMSO)£173.00
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TAR-T3455-10mg10mg£189.00
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TAR-T3455-25mg25mg£285.00
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TAR-T3455-50mg50mg£430.00
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TAR-T3455-100mg100mg£582.00
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TAR-T3455-500mg500mg£1,139.00
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Further Information

Bioactivity:
LY2801653 is an orally available, small molecule inhibitor of the proto-oncogene c-Met (Ki: 2 nM) with potential antineoplastic activity. LY2801653 selectively binds to c-Met, thereby inhibiting c-Met phosphorylation and disrupting c-Met signal transduction pathways. This may induce cell death in tumor cells overexpressing c-Met protein or expressing the constitutively activated c-Met protein.
CAS:
1206799-15-6
Formula:
C30H22F2N6O3
Molecular Weight:
552.542
Pathway:
Tyrosine Kinase/Adaptors; Angiogenesis; Immunology/Inflammation
Purity:
0.9956
SMILES:
Cc1ccc(C(=O)Nc2ccc(Oc3cc4cnn(C)c4cc3-c3cn[nH]c3)c(F)c2)c(=O)n1-c1ccc(F)cc1
Target:
Discoidin Domain Receptor (DDR); FLT; c-Met/HGFR; ROS; ROS Kinase

References

Yan SB, et al. Invest New Drugs. 2013, 31(4):833-44.